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Information Systems Security Engineer Jobs

20 Job Offers

Information Systems Security Engineer
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Seeking an Information Systems Security Engineer (ISSE) to secure AI-enabled capabilities and national defense systems at Fort Meade. You will lead RMF authorization packages, ATOs, and vulnerability remediation using ACAS, SCAP, and eMASS. Expertise in STIGs, IAVM directives, and cybersecurity d...
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United States , Fort Meade
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99000.00 - 225000.00 USD / Year
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Booz Allen Hamilton
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Information Systems Security Engineer 3 (FORECASTED)
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Seeking a seasoned Information Systems Security Engineer (ISSE) with 20+ years of experience for a critical role in Annapolis Junction. You will perform technical security assessments, validate IA compliance, and integrate security into multi-enclave environments. Requires DoD 8570 IASAE Level 3,...
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United States , Annapolis Junction
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189000.00 - 260000.00 USD / Year
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Columbia Technology Partners
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Information Systems Security Engineer 3
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Senior Information Systems Security Engineer (ISSE) with 20+ years of experience needed in Annapolis Junction. Must hold CISSP, ISSEP, and DoD 8570 IASAE Level 3 certifications. You will perform technical security assessments, design secure architectures, and ensure IA compliance across multi-enc...
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USA , Annapolis Junction
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189000.00 - 260000.00 USD / Year
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Columbia Technology Partners
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Information Systems Security Engineer Senior Level
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Senior-Level Information Systems Security Engineer (ISSE) needed in Ft. Meade. Requires TS/SCI with FSP Polygraph, 20+ years of ISSE experience, and DoD 8570 IASAE Level 3 compliance with CISSP and ISSEP certifications. You will lead RMF processes, C&A documentation, and security control assessme...
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Location
United States , Ft. Meade
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Not provided
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Integrity Technology Consultants
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Information Systems Security Engineer 3 - TS/SCI With Poly
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Amentum seeks a senior Information Systems Security Engineer (ISSE) 3 in Columbia, MD. This role requires 20+ years of experience with Cybersecurity principles, PKI, and network security architecture. You will lead security engineering for complex systems, enforcing trusted relationships and secu...
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United States , Linthicum
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220000.00 - 270000.00 USD / Year
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Amentum
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Principal, Systems and Infrastructure Engineer, Information Security
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Principal Cloud Infrastructure & Platform Engineer leading multi-cloud migration (AWS, GCP, Azure) at Walmart/VIZIO in Denver. This hands-on role requires expertise in Terraform, Python, and Bash automation to design scalable, secure architectures. Drive modernization, FinOps, and governance whil...
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United States of America , Denver
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121000.00 - 242000.00 USD / Year
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Walmart
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Information System Security Engineer (ISSE) / Cybersecurity Systems Engineer (TS Cleared)
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Seeking an Information System Security Engineer (ISSE) / Cybersecurity Systems Engineer with an active Top Secret clearance in Quantico, VA. You will manage IT infrastructure, ensure system uptime, and enforce security compliance. Requires a Bachelor’s degree or equivalent experience, 5+ years in...
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United States , Quantico
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Not provided
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NTT DATA
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Information Systems Security Engineer 3
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Seeking an experienced Information Systems Security Engineer 3 (ISSE) in Annapolis Junction, MD. Requires 20+ years of experience, DoD 8570 IASAE Level 3, and active TS/SCI with Polygraph. You will lead security assessments, integrate IA into complex systems, and enforce trusted architectures. En...
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USA , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Information Systems Security Engineer (ISSE)
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Seeking an Information Systems Security Engineer (ISSE) in Washington, DC, to design and implement secure systems across the full SDLC. This role requires a Master’s degree, 10+ years of IT/IS experience, and an active Top Secret clearance. You will translate NIST and federal requirements into te...
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United States , Washington
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Not provided
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NTT DATA
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Information Systems Security Engineer 3
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Join our team as an Information Systems Security Engineer 3 in Annapolis Junction. This role requires 20 years of ISSE experience, a Bachelor's degree, CISSP/ISSEP certifications, and an active Security Clearance. You will conduct security assessments, design secure architectures, and ensure IA c...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Cleared On Site Information Systems Security Engineer - SME
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Seeking a Cleared On-Site IS Security Engineer (SME) with an Active TS/SCI clearance. This role requires 10+ years of experience securing information systems within DoD/IC environments. You will apply deep expertise in network security, encryption, and vulnerability assessment using tools like SI...
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United States
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Not provided
SMX Corporation
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Information Systems Security Engineer
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United States , Huntsville
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Not provided
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Yulista Holdings
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Information Systems Security Engineer 3
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United States , Linthicum, Maryland
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Salary
220000.00 - 270000.00 USD / Year
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Amentum
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System Engineer - Information Systems Security Officer
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United States , Annapolis Junction
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150000.00 - 200000.00 USD / Year
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Synergy ECP
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Information Systems Security Engineer 3
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Seeking an experienced Information Systems Security Engineer 3 in Annapolis Junction. This role requires 20 years' ISSE experience, a relevant Bachelor's degree, CISSP/ISSEP certifications, and an active clearance. You will conduct security assessments, design secure architectures, and ensure IA ...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Information Systems Security Engineer (ISSE) - SME
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United States , Washington
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Not provided
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NTT DATA
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Senior Information Systems Security Engineer
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Seeking a Senior ISSE with 20+ years' experience to lead security engineering for complex federal systems in Annapolis Junction. Must hold an active clearance, IASAE III compliance (CISSP/ISSEP), and expertise in the RMF. We offer top-tier medical/dental/vision, a 6% 401k match, and significant s...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Information Systems Security Engineer Level 2
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Seeking an experienced Information Systems Security Engineer (ISSE) Level 2 in Annapolis Junction. This role requires a U.S. citizen with an active clearance, IASAE II compliance, and 12+ years' experience in secure system design and cybersecurity assessments. You will lead security engineering f...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Information Systems Security Engineer Level 2
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Seeking an experienced ISSE Level 2 in Annapolis Junction to design and integrate security architectures for complex systems. Requires 12 years' ISSE experience, a relevant degree, DoD 8570 IASAE II compliance, and an active clearance. Enjoy top-tier medical plans, a 6% 401k match, and generous c...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Senior Information Systems Security Engineer
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Seeking a Senior Information Systems Security Engineer in Annapolis Junction. This role requires 20 years of ISSE experience, a relevant degree, and U.S. citizenship. You will design, integrate, and validate security systems for complex computing environments. We offer top-tier medical plans, a 6...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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About the Information Systems Security Engineer role

Explore a rewarding career in cybersecurity by discovering Information Systems Security Engineer jobs. This critical profession sits at the intersection of technology, risk management, and strategic defense, tasked with designing, implementing, and maintaining the security posture of an organization's entire digital infrastructure. Professionals in this role are the architects and guardians of information security, building resilient systems to protect sensitive data, networks, and applications from ever-evolving threats. Their work is fundamental to business continuity, regulatory compliance, and maintaining trust in the digital age.

The typical responsibilities of an Information Systems Security Engineer are comprehensive and multifaceted. They conduct thorough risk assessments and vulnerability analyses to identify security gaps within systems. A core function involves designing and engineering security solutions, which may include deploying and configuring firewalls, intrusion detection/prevention systems (IDS/IPS), encryption tools, and advanced identity and access management (IAM) platforms. Engineers enforce security policies, ensuring the principle of least privilege and implementing robust authentication mechanisms like multi-factor authentication (MFA). They are deeply involved in the security development lifecycle, reviewing architecture and code for potential weaknesses. Furthermore, they lead incident response activities, perform forensic analysis after security breaches, and develop comprehensive disaster recovery and business continuity plans. A significant part of the role also involves ensuring adherence to industry frameworks and standards such as NIST, ISO 27001, SOC 2, and GDPR, often preparing systems for audits and certifications.

To excel in Information Systems Security Engineer jobs, individuals must possess a blend of deep technical knowledge and analytical prowess. A strong foundation in networking protocols, operating systems (Windows, Linux), cloud security (AWS, Azure, GCP), and scripting languages (Python, PowerShell) is essential. Familiarity with security concepts like Zero Trust architecture, threat modeling, and penetration testing methodologies is highly valued. Employers typically seek candidates with a bachelor’s degree in cybersecurity, computer science, information technology, or a related field, though equivalent experience is often considered. Professional certifications such as CISSP, CISM, CEH, CompTIA Security+, or vendor-specific credentials are frequently required or strongly preferred to validate expertise. Beyond technical skills, successful engineers demonstrate strong problem-solving abilities, meticulous attention to detail, effective communication skills to explain complex risks to non-technical stakeholders, and a proactive, vigilant mindset to anticipate new threats.

The demand for skilled Information Systems Security Engineers continues to surge across all sectors, including finance, healthcare, government, and technology. These jobs offer the opportunity to work on cutting-edge security challenges, from cloud migration security to implementing Zero Trust models, making it a dynamic and impactful career path for those passionate about defending digital assets and shaping a more secure technological future.