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Information System Security Officer Jobs (On-site work)

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Information Systems Security Officer Level 3
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Seeking an experienced Information Systems Security Officer (ISSO) Level 3 in Annapolis Junction. This role ensures system compliance with NIST RMF and DoD policies, requiring 10 years' IT/cybersecurity experience and IAM I certification. Enjoy top-tier benefits including fully paid dental/vision...
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United States , Annapolis Junction
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Columbia Technology Partners
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Information Systems Security Officer
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Join AnaVation as a mid-level ISSO in Washington, DC. Provide security compliance expertise on critical projects, utilizing your NIST and FISMA experience. This role requires a Top-Secret clearance, on-site work, and focuses on SA&A packages and risk assessments. We offer competitive pay, generou...
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United States , Washington
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AnaVation
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Junior Information System Security Officer
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Launch your cybersecurity career as a Junior ISSO in Washington, DC. Support RMF compliance, ATO packages, and security monitoring for federal systems using tools like JCAM and Tenable. This role offers competitive pay, generous benefits, and a mission-driven environment to grow your GRC expertise.
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United States , Washington, DC
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AnaVation
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Mid-Level Information System Security Officer
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Join AnaVation's cybersecurity team in Washington, DC as a Mid-Level ISSO. Utilize your RMF expertise to manage ATOs, conduct security assessments, and ensure NIST compliance for federal systems. This role offers competitive pay, generous benefits, and requires a relevant degree, 4+ years' experi...
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United States , Washington, DC
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AnaVation
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Senior Information System Security Officer
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Lead critical cybersecurity efforts as a Senior ISSO in Washington, DC. This role requires expert RMF/NIST knowledge to manage ATO processes for high-impact federal systems. Mentor junior staff and ensure compliance while enjoying top-tier benefits like a 401k match and comprehensive health cover...
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United States , Washington
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AnaVation
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Information System Security Officer
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Join our cybersecurity team as an Information System Security Officer (ISSO) in Washington, DC. You will directly own the ATO process, ensuring compliance with NIST standards and managing POA&Ms. This role requires an active Top Secret/SCI clearance, IAT II certification, and experience with eMAS...
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United States , Washington, DC
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Barbaricum
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Senior Information Systems Security Officer
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Join 2HB Incorporated as a Senior ISSO in Annapolis Junction, MD. This role requires a TS/SCI/Full Scope Polygraph and DoD 8570 IAM Level II/IAT Level III certification (e.g., CISSP). You will enforce security policies, maintain operational posture, and perform risk assessments for critical IC/Do...
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United States , Annapolis Junction
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2HB
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Senior Information Systems Security Officer
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Join 2HB Incorporated as a Senior ISSO in Annapolis Junction, MD. This role requires a TS/SCI/Full Scope Polygraph, DoD 8570 IAM Level II/IAT Level III certification, and 12+ years of experience. You will enhance security posture, oversee system operations, and manage accreditation for critical I...
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United States , Annapolis Junction
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2HB
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Information Systems Security Officer Level 3
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Seeking an experienced Information Systems Security Officer (ISSO) Level 3 in Annapolis Junction. You will maintain operational security, enforce policies, and perform risk assessments for classified systems. Requires 10 years in IT/cybersecurity, a relevant Bachelor's degree, and expertise in se...
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United States , Annapolis Junction
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Columbia Technology Partners
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Information Systems Security Officer
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Seeking an experienced ISSO to lead cybersecurity compliance for the AFRL's RISE contract at Kirtland AFB, NM. This role requires an active TS/SCI clearance, CISSP, and 5+ years of DoD RMF experience. You will manage A&A packages, security controls, and risk assessments for critical space systems...
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United States , Albuquerque, New Mexico
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Astrion
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Cybersecurity - Information System Security Officer
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Join Boeing's Classified Cybersecurity team as an Information System Security Officer (ISSO). This role requires an active Top Secret clearance, IAM Level 1 certification, and 3+ years of RMF experience. You will lead A&A processes and ensure security compliance for classified systems in Berkeley...
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United States , Berkeley; Hazelwood; Saint Charles
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105400.00 - 142600.00 USD / Year
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Boeing
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Explore a critical and in-demand career path by searching for Information System Security Officer jobs. An Information System Security Officer (ISSO) is a cybersecurity professional responsible for ensuring that an organization's information systems are designed, operated, and maintained in a secure and compliant manner. These roles are fundamental within government agencies, defense contractors, and any private sector company handling sensitive data. ISSOs act as the central point of accountability for the security posture of assigned systems, bridging the gap between technical teams, management, and compliance authorities. Professionals in these jobs typically manage the entire lifecycle of system security authorization. A core responsibility is guiding systems through formal compliance frameworks like the National Institute of Standards and Technology (NIST) Risk Management Framework (RMF) to achieve and maintain an Authority to Operate (ATO). This involves developing and maintaining critical documentation such as System Security Plans (SSPs), conducting continuous risk assessments, and managing Plans of Action and Milestones (POA&Ms) to address vulnerabilities. ISSOs continuously monitor systems for security threats, ensure timely patching of vulnerabilities, and verify that security controls are operating effectively. They serve as key advisors, interpreting complex security regulations for engineering and development teams to ensure secure design principles are integrated from the outset, often within modern DevOps or cloud environments. Typical skills and requirements for Information System Security Officer jobs are both technical and regulatory. A strong foundation in networking, system administration, and cloud security (AWS, Azure, GCP) is highly valued. Candidates must possess deep knowledge of security frameworks such as NIST SP 800-53, FISMA, and DISA STIGs. Essential duties include conducting security control assessments, analyzing vulnerability scans from tools like Tenable Nessus, and enforcing secure configurations. On the compliance side, expertise in the accreditation process using platforms like eMASS is common. Excellent communication and documentation skills are paramount, as ISSOs must clearly articulate risks and requirements to both technical and non-technical stakeholders. Common prerequisites for these positions include a bachelor’s degree in cybersecurity, information technology, or a related field, though equivalent experience is often accepted. Industry-standard certifications are frequently required to validate expertise, such as CompTIA Security+, Certified Information Systems Security Professional (CISSP), or Certified Information Security Manager (CISM). For roles supporting government and defense contracts, U.S. citizenship and the ability to obtain and maintain a security clearance are typical necessities. If you are a detail-oriented professional passionate about protecting critical assets and navigating the intersection of technology, risk, and compliance, exploring Information System Security Officer jobs could be your next career move. This profession offers a dynamic career with significant impact, ensuring the resilience and security of vital information infrastructure.

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