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Information System Security Officer United States Jobs

20 Job Offers

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Information System Security Officer (ISSO) Mid - Top Secret Clearance Required
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120000.00 - 135000.00 USD / Year
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Information System Security Officer (ISSO) Senior - Top Secret Clearance Required
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United States, Quantico
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130000.00 - 145000.00 USD / Year
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Information System Security Officer - ISSO (PL)
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United States, Eglin AFB
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Not provided
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Principal Information System Security Officer
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FedRAMP Information System Security Officer (ISSO)
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FedRAMP Information System Security Officer (ISSO)
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FedRAMP Information System Security Officer (ISSO)
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FedRAMP Information System Security Officer (ISSO)
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Information System Security Officer (ISSO)
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Senior ISSO role in Washington, DC requiring 6+ years of NIST, FISMA, and RMF experience plus CISSP certification. Join AnaVation to lead security assessments, FedRAMP compliance, and ATO processes for federal intelligence missions.
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85933.19 - 202292.42 USD / Year
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Information System Security Officer
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AM Pierce & Associates seeks an Information System Security Officer in St. Inigoes, MD. Requires 2+ years of ISSO/cybersecurity experience, RMF and NIST 800-53 knowledge, eMASS proficiency, and an active DoD Secret clearance.
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Location
United States, St. Inigoes
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80000.00 - 130000.00 USD / Year
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Information Security System Officer (ISSO)
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Applied Intuition seeks an ISSO in Poway, CA to maintain accredited classified systems and author RMF artifacts. Requires 5+ years cybersecurity experience, Security+ certification, and hands-on NESSUS, ACAS, and STIG expertise.
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Information System Security Officer 3
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United States, Ft. Meade
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Information System Security Officer (ISSO) - FULLY CLEARED with POLYGRAPH REQUIRED
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Information System Security Officer - Senior
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Senior Information System Security Officer (ISSO) needed at Eglin AFB, FL to lead cybersecurity for the 45th Test Squadron’s RDT&E enclaves. Requires a Top-Secret clearance, CISSP/CISM, and 10+ years of experience with RMF and DoD cybersecurity policies. You will advise on system lifecycle securi...
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Journeyman Information System Security Officer
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Seeking a Journeyman Information System Security Officer (ISSO) at Hill AFB, Utah. This role supports the Aerospace Dominance Enabler Division, ensuring Air Force systems meet DoD cybersecurity requirements and RMF compliance. Requires an active Secret clearance, IAT Level II certification, and e...
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United States, Hill AFB
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Journeyman Information System Security Officer
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Astrion seeks a Journeyman ISSO at Hill AFB, Utah, to safeguard critical Air Force systems. You will enforce cybersecurity policies, conduct risk assessments, and support RMF accreditation. Requires an active Secret clearance, IAT Level II certification, and US citizenship. Enjoy competitive pay,...
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United States, Hill AFB
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Information System Security Officer (ISSO)
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Astrion seeks an Information System Security Officer (ISSO) at Eglin AFB, FL, to oversee cybersecurity for critical mission systems. You will execute the RMF lifecycle, manage SSPs and POA&Ms, and secure ATOs. Requires an active SECRET clearance, CompTIA Security+, and 3-10 years of experience. E...
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Information System Security Officer (ISSO)
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DCS is seeking an Information System Security Officer (ISSO) to support the AFLCMC/C3BM division at Hill AFB in Ogden, Utah. This role requires an Active Secret Clearance, IAT Level II certification, and 8+ years of experience, including DoD cybersecurity compliance. You will lead RMF accreditati...
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Information System Security Officer (ISSO)
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Astrion seeks a Mid-Level Information System Security Officer (ISSO) at Eglin AFB, FL. This full-time role requires an Active Top Secret clearance and DoD 8140 IAT Level II certification. You will support the 46 Test Squadron by performing cybersecurity duties, producing RMF documentation, and co...
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Journeyman Information System Security Officer
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Astrion seeks a Journeyman ISSO at Hill AFB, Utah, to secure critical Air Force systems. You will support RMF accreditation, conduct risk assessments, and enforce cybersecurity policies using eMASS. Requires a Secret clearance, IAT Level II certification, and 3+ years of DoD experience. Enjoy com...
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United States, Hill AFB
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About the Information System Security Officer role

Explore a critical and in-demand career path by searching for Information System Security Officer jobs. An Information System Security Officer (ISSO) is a cybersecurity professional responsible for ensuring that an organization's information systems are designed, operated, and maintained in a secure and compliant manner. These roles are fundamental within government agencies, defense contractors, and any private sector company handling sensitive data. ISSOs act as the central point of accountability for the security posture of assigned systems, bridging the gap between technical teams, management, and compliance authorities.

Professionals in these jobs typically manage the entire lifecycle of system security authorization. A core responsibility is guiding systems through formal compliance frameworks like the National Institute of Standards and Technology (NIST) Risk Management Framework (RMF) to achieve and maintain an Authority to Operate (ATO). This involves developing and maintaining critical documentation such as System Security Plans (SSPs), conducting continuous risk assessments, and managing Plans of Action and Milestones (POA&Ms) to address vulnerabilities. ISSOs continuously monitor systems for security threats, ensure timely patching of vulnerabilities, and verify that security controls are operating effectively. They serve as key advisors, interpreting complex security regulations for engineering and development teams to ensure secure design principles are integrated from the outset, often within modern DevOps or cloud environments.

Typical skills and requirements for Information System Security Officer jobs are both technical and regulatory. A strong foundation in networking, system administration, and cloud security (AWS, Azure, GCP) is highly valued. Candidates must possess deep knowledge of security frameworks such as NIST SP 800-53, FISMA, and DISA STIGs. Essential duties include conducting security control assessments, analyzing vulnerability scans from tools like Tenable Nessus, and enforcing secure configurations. On the compliance side, expertise in the accreditation process using platforms like eMASS is common. Excellent communication and documentation skills are paramount, as ISSOs must clearly articulate risks and requirements to both technical and non-technical stakeholders.

Common prerequisites for these positions include a bachelor’s degree in cybersecurity, information technology, or a related field, though equivalent experience is often accepted. Industry-standard certifications are frequently required to validate expertise, such as CompTIA Security+, Certified Information Systems Security Professional (CISSP), or Certified Information Security Manager (CISM). For roles supporting government and defense contracts, U.S. citizenship and the ability to obtain and maintain a security clearance are typical necessities. If you are a detail-oriented professional passionate about protecting critical assets and navigating the intersection of technology, risk, and compliance, exploring Information System Security Officer jobs could be your next career move. This profession offers a dynamic career with significant impact, ensuring the resilience and security of vital information infrastructure.