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Information System Security Engineer Jobs

8 Job Offers

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Information System Security Engineer
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Astrion seeks an Information System Security Engineer in El Segundo, CA to support Space Systems Command. You will lead Assessment & Authorization (A&A) and RMF processes using eMASS for next-gen space systems. Requires a Top Secret clearance, 5+ years in IA, and CompTIA Security+. Enjoy competit...
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United States , El Segundo
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Salary
130000.00 USD / Year
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Astrion
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Until further notice
Information System Security Engineer - Senior
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Senior Information System Security Engineer (ISSE) sought to lead enterprise security toolset optimization for a critical government program in Warrenton, VA. Requires active Top-Secret/SCI clearance, expertise in Trellix/ePO and ACAS/Nessus, plus Splunk experience. Design secure architectures, e...
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United States , Warrenton
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Salary
185000.00 USD / Year
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Amentum
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Until further notice
System Engineer II, Infrastructure Cloud Delivery Security - Information Solutions
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Join MUSC as a System Engineer II in Infrastructure Cloud Delivery Security, supporting academic, research, and healthcare missions in Charleston, SC. You will develop, implement, and maintain Hosting Services server systems while providing proactive technical support and collaborative solutions....
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United States , Charleston
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Not provided
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MUSC Health
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Until further notice
Information System Security Engineer - Senior
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Senior Information System Security Engineer sought by Amentum in San Antonio, TX. Must hold an active Top-Secret/SCI clearance and possess deep expertise in Splunk, ACAS/Nessus, and Trellix. You will design security controls, manage cyber tools, and ensure JSIG compliance for a critical IT progra...
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United States , San Antonio
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Salary
160000.00 - 175000.00 USD / Year
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Amentum
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Until further notice
Information System Security Engineer (ISSE) / Cybersecurity Systems Engineer (TS Cleared)
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Seeking an Information System Security Engineer (ISSE) / Cybersecurity Systems Engineer with an active Top Secret clearance in Quantico, VA. You will manage IT infrastructure, ensure system uptime, and enforce security compliance. Requires a Bachelor’s degree or equivalent experience, 5+ years in...
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Location
United States , Quantico
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Not provided
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NTT DATA
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Until further notice
System Engineer - Information Systems Security Officer
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Location
United States , Annapolis Junction
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Salary
150000.00 - 200000.00 USD / Year
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Synergy ECP
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Senior Information System Security Engineer
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Seeking a Senior Information System Security Engineer with an active Top Secret/SCI clearance and CISSP certification. This role at Hanscom AFB, MA, provides enterprise security support for critical Air Force C3I infrastructure. Requires 10+ years' experience, IAT Level II, and expertise in A&A, ...
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United States , Bedford / Hanscom AFB, Massachusetts
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Salary
160000.00 - 175000.00 USD / Year
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Astrion
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Until further notice
Information System Security Engineer (ISSE), Journeyman
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Seeking an ISSE Journeyman to support RMF A&A packages for tactical systems at Webster Outlying Field. This role requires a Bachelor's degree, Security+ or equivalent certification, and 3-7 years of RMF/eMASS experience. We offer comprehensive benefits, including medical coverage, tuition reimbur...
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United States , St. Inigoes
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Salary
80000.00 - 90000.00 USD / Year
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KAIROS Inc
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Until further notice

About the Information System Security Engineer role

Explore a dynamic and critical career path by searching for Information System Security Engineer jobs. This profession sits at the forefront of cybersecurity, dedicated to designing, implementing, and maintaining the robust security architectures that protect an organization's most vital digital assets and data. Professionals in this role are the architects and builders of cyber defense, translating security policies into technical reality. They work to ensure the confidentiality, integrity, and availability of information systems by proactively identifying vulnerabilities, engineering solutions to mitigate threats, and ensuring compliance with stringent security standards.

The typical responsibilities of an Information System Security Engineer are comprehensive and technical. They commonly involve designing and deploying security solutions such as firewalls, intrusion detection/prevention systems (IDS/IPS), and encryption tools. A significant part of the role focuses on identity and access management, implementing frameworks like Zero Trust, Privileged Access Management (PAM), and multi-factor authentication (MFA) to enforce least-privilege principles. These engineers conduct regular security assessments, vulnerability scans, and penetration testing to identify weaknesses. They are also responsible for developing and maintaining critical documentation, including System Security Plans (SSPs), security policies, and procedures to support compliance with frameworks like the Risk Management Framework (RMF), NIST standards, or ISO 27001. Furthermore, they play a key role in incident response, providing engineering expertise to contain breaches and redesign systems to prevent future attacks.

To succeed in Information System Security Engineer jobs, a specific blend of education, skills, and experience is required. A bachelor's or master's degree in cybersecurity, information technology, computer science, or a related engineering field is typically expected. Employers seek candidates with hands-on technical expertise in networking, operating systems (Windows, Linux), and cloud platforms (AWS, Azure, GCP). Proficiency with security technologies for PAM, identity governance, SIEM integration, and endpoint protection is highly valued. Strong analytical and problem-solving skills are essential for assessing complex systems and designing effective controls. Given the need to align technical measures with regulatory requirements, a deep understanding of relevant security frameworks and controls is crucial. Professional certifications such as CISSP, CISM, Security+, or vendor-specific credentials are often required or strongly preferred to validate expertise. For roles in government or defense contracting, eligibility for security clearances may be a standard requirement.

The demand for skilled Information System Security Engineers continues to grow across all sectors, from finance and healthcare to government and technology. These jobs offer the opportunity to work on cutting-edge security challenges, from implementing Zero Trust architectures to securing hybrid cloud environments. If you are a technically adept professional passionate about building resilient systems and staying ahead of cyber threats, exploring Information System Security Engineer jobs can lead to a rewarding and impactful career securing the digital landscape.