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Engineer United States, Holly Springs Jobs

19 Job Offers

6243 - Downstream Principal Engineer / Lead Validation Engineer
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Covex
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6242 - Upstream Principal Engineer / Lead Validation Engineer
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Covex
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Senior Engineer – Global Engineering – Clean & Plant Utilities
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115494.60 - 156257.40 USD / Year
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Amgen
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Senior Manufacturing Systems Engineer – DeltaV Batch
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Senior Manufacturing Systems Engineer – DeltaV Batch sought for Amgen’s newest, advanced drug substance plant in Holly Springs, NC. Lead automation innovation for upstream/downstream processes using Emerson DeltaV, OPC, and Foundation Fieldbus. Drive engineering projects for a state-of-the-art Fl...
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136906.95 - 185227.05 USD / Year
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Amgen
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Process Engineer - Solution Prep, Upstream, and Downstream
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Join a top-tier biopharma team as a **Process Engineer** in Holly Springs, NC. You will design, commission, and qualify GMP systems for drug substance production, specializing in **Solution Prep, Upstream, and Downstream** processes. Ideal candidates hold a degree in Chemical/Mechanical Engineeri...
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88281.00 - 119439.00 USD / Year
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Amgen
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Senior Process Engineer
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Senior Process Engineer sought for Amgen’s cutting-edge AmgenFleXBatch facility in Holly Springs, NC. Join the Facilities & Engineering team to design, commission, and qualify downstream biopharmaceutical equipment. Requires a Chemical/Mechanical Engineering degree and 5+ years in GMP biopharma o...
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115494.60 - 156257.40 USD / Year
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Amgen
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Manufacturing Systems Engineer: Automation - Delta V
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Amgen
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Clean Utilities Sr Engineer
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Amgen seeks a Clean Utilities Sr Engineer in Holly Springs, NC, to lead utility systems supporting life-saving biotech manufacturing. You will provide engineering ownership for Clean Steam, Pharmaceutical Water, and HVAC systems, driving improvements and ensuring GMP compliance. Ideal candidates ...
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115494.60 - 156257.40 USD / Year
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Amgen
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Process Analytical Engineer
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Amgen seeks a Process Analytical Engineer in Holly Springs, NC, to join the Facilities & Engineering group. You will ensure cGMP lab system qualification, calibration, and reliability, performing hands-on troubleshooting and root cause analysis. This role requires a Master’s degree or equivalent ...
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88281.00 - 119439.00 USD / Year
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Amgen
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Senior Manufacturing Systems Engineer - PLC Systems
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Senior Manufacturing Systems Engineer (PLC Systems) sought by Amgen in Holly Springs, NC. Drive automation solutions for GMP biopharmaceutical production, integrating Rockwell platforms and OEM software. Leverage 4+ years of engineering experience to support capital projects, commissioning, and p...
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136906.95 - 185227.05 USD / Year
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Amgen
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Sr Engineer I, Process Development (Downstream)
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Join Amgen as a Sr. Engineer I, Process Development (Downstream) in Holly Springs, NC. You will lead technology transfer, process optimization, and validation for our FleX Batch facility. Leverage your expertise in biologics purification and cGMP to drive yield improvement and complex investigati...
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115494.60 - 156257.40 USD / Year
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Amgen
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Sr Engineer, PD Process Validation & Business Strategy
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Sr Engineer, PD Process Validation & Business Strategy at Amgen’s FleX Batch facility in Holly Springs, NC. Lead PPQ strategy, tech transfer, and business optimization for commercial biologics. Requires 4+ years in process development/validation with upstream/downstream expertise. Enjoy a compreh...
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115494.60 - 156257.40 USD / Year
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Amgen
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Sr Engineer, Process Development
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Amgen seeks a Sr Engineer, Process Development in Holly Springs, NC to drive innovation in biologics manufacturing. You will apply scientific principles to upstream and harvest processes, supporting tech transfer, troubleshooting, and next-gen technology development. Ideal candidates have 4+ year...
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115494.60 - 156257.40 USD / Year
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Amgen
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Senior Electrical Engineer - Power Systems
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Senior Electrical Engineer sought for Amgen’s Holly Springs site to lead capital project electrical design and commissioning. You will steer planning, equipment selection, and construction support for process and utility systems. Requires a Bachelor’s degree with 4 years of engineering experience...
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115494.60 - 156257.40 USD / Year
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Amgen
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Manufacturing Systems Engineer: Automation
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Seeking a Manufacturing Systems Engineer: Automation in Holly Springs, NC. You will develop and maintain process control systems on the Emerson DeltaV DCS for GMP biopharmaceutical production. Requires a degree in Engineering or related field with experience in automation system design and troubl...
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105362.60 - 142549.40 USD / Year
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Amgen
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Manufacturing Systems Engineer: Automation
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Join Amgen as a Manufacturing Systems Engineer: Automation in Holly Springs, NC. You will develop and maintain Emerson DeltaV DCS systems, collaborating with stakeholders to optimize process automation in a GMP biopharmaceutical environment. Ideal candidates have a degree in Engineering or relate...
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105362.60 - 142549.40 USD / Year
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Amgen
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Senior Manufacturing Systems Engineer: Automation
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Join Amgen as a Senior Manufacturing Systems Engineer: Automation in Holly Springs, NC. You will develop and maintain Emerson DeltaV DCS for our advanced FleXbatch facility. Ideal candidates have a degree in Engineering and GMP biopharmaceutical automation experience. Enjoy a comprehensive benefi...
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Amgen
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Senior Manufacturing Systems Engineer: Automation (Wednesday - Saturday Shift)
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Join Amgen’s cutting-edge Holly Springs facility as a Senior Manufacturing Systems Engineer (Automation) on a Wednesday-Saturday shift. You’ll develop and maintain Emerson DeltaV DCS systems, transforming process requirements into digital solutions in a GxP environment. Ideal candidates bring 4+ ...
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136906.95 - 185227.05 USD / Year
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Amgen
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Process Engineer - Solution Preparation
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Join a top-tier biopharmaceutical team as a **Process Engineer** in Holly Springs, NC, focusing on **Solution Preparation** equipment. You will support design, commissioning, and qualification of single-use mixers, CIP/SIP skids, and vessels for drug substance production. Ideal candidates bring a...
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115494.60 - 156257.40 USD / Year
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Amgen
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About the Engineer role

Engineer jobs represent a cornerstone of the operational and technical workforce, focused on the application of scientific and mathematical principles to design, develop, maintain, and improve systems, structures, and processes. While the field is incredibly diverse, spanning disciplines from civil and software to mechanical and electrical engineering, the core mission remains consistent: to solve complex problems and ensure functionality, efficiency, and safety. Professionals in these roles are the backbone of infrastructure, technology, and innovation, turning theoretical concepts into practical, working solutions that power our modern world.

Individuals in these positions typically engage in a wide array of responsibilities. A primary function involves the installation, maintenance, and preventative care of tools, equipment, and complex systems. This includes routine inspections, calibrating controls and gauges, and performing diagnostic tests to ensure everything operates within specified parameters. Troubleshooting is a daily activity, requiring engineers to identify the root cause of malfunctions and execute repairs, whether it's a mechanical failure, an electrical issue, or a problem with plumbing and HVAC systems. For those in supervisory engineer jobs, responsibilities expand to include leading teams, which involves hiring, training, scheduling, and mentoring other engineering staff to ensure a high standard of work and team cohesion.

The skill set required for engineer jobs is both broad and technical. A strong foundation is typically built through vocational, technical, or trade school education, providing essential knowledge in relevant engineering principles. Practical, hands-on experience is highly valued, often requiring several years in a related field. Key technical skills include proficiency in reading blueprints and schematics, a solid understanding of mechanical, electrical, and plumbing (MEP) systems, and the safe operation of hand and power tools. Many roles also require specific certifications, such as universal CFC handling licenses, to comply with safety and environmental regulations.

Beyond technical prowess, successful candidates for engineer jobs possess strong problem-solving abilities, acute attention to detail, and a steadfast commitment to safety protocols. They must be able to communicate clearly with team members and other departments, document their work accurately, and manage inventory of parts and supplies. Physical stamina is often necessary, as the role can involve standing for extended periods, lifting heavy objects, and working in confined spaces. A methodical and proactive approach is essential, focusing not just on fixing current issues but on implementing preventative measures to avoid future problems. For those seeking stable, hands-on, and critically important careers, engineer jobs offer a rewarding path with opportunities for continuous learning and advancement into leadership positions.