A Dermatopathologist with General Surgical Sign-Out is a highly specialized physician who operates at the critical intersection of dermatology and pathology, with the added capability of diagnosing a broad range of tissue specimens. This dual-expertise role is central to accurate patient diagnosis and treatment planning. Professionals in this field are first and foremost anatomic pathologists, trained to examine tissues removed during surgeries and biopsies. Their unique value lies in their subspecialty fellowship training in dermatopathology, granting them deep expertise in diagnosing diseases of the skin, hair, and nails, which are among the most common specimens in any pathology practice. However, their responsibilities extend beyond the derm bench; they are also proficient in the "general surgical sign-out" of cases from various organ systems, such as gastrointestinal, genitourinary, gynecologic, and breast pathology. The core responsibility is the comprehensive diagnostic interpretation of complex biopsy and cytology material. This involves meticulous gross examination of specimens, microscopic evaluation of tissue slides, integration of clinical information, and the synthesis of a definitive diagnosis. The pathologist dictates a detailed report that becomes a permanent part of the patient's medical record, directly guiding treatment decisions by oncologists, surgeons, and dermatologists. Beyond case sign-out, typical duties include participating in quality assurance and peer review programs, consulting with colleagues on challenging cases, and communicating directly with referring physicians to discuss diagnostic findings and their implications. They also play a key educational role, mentoring residents and fellows and contributing to the continuing education of the clinical staff. To qualify for these specialized jobs, candidates must complete extensive medical training. This includes a Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree, followed by residency training in Anatomic and Clinical Pathology (AP/CP) and board certification. Crucially, they must then complete a fellowship in dermatopathology and obtain subspecialty board certification or eligibility. A state medical license is mandatory. The most sought-after professionals for these jobs possess not only this rigorous certification but also a keen diagnostic eye, exceptional attention to detail, strong communication skills for effective interdisciplinary collaboration, and the ability to thrive in a high-volume laboratory environment. The demand for such versatile diagnosticians is steady, as healthcare institutions and large reference laboratories seek experts who can manage a high-throughput derm practice while providing essential coverage for general surgical pathology cases, making this a stable and rewarding career path for qualified physicians.