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Applied Scientist United States Jobs (Hybrid work)

85 Job Offers

Applied Scientist
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Join AWS Agentic AI as an Applied Scientist in Santa Clara, CA. You'll build next-gen models for intelligent automation, solving real-world problems with vast data and computational resources. Requires a PhD/MSc, 3+ years in ML, and publications at top conferences. Enjoy health insurance, 401(k) ...
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United States , Santa Clara
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171600.00 - 222200.00 USD / Year
Amazon
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Applied Scientist II
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Join Uber’s Brand Science team as an Applied Scientist II in New York or San Francisco. You’ll tackle complex causal inference and experimental design challenges to optimize a large marketing budget. Leverage Python, R, and SQL on rich datasets to shape strategy and drive measurable impact. Enjoy...
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United States , New York, New York; San Francisco, California
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161000.00 - 179000.00 USD / Year
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Uber
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Applied Scientist Ii
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Join Microsoft AI in Redmond as an Applied Scientist II to advance generative search with LLMs like Qwen and Llama. You’ll build production ML models, optimize large-scale systems, and drive insights from petabytes of data. Ideal for experts in Machine Learning, Agentic Modeling, or Data Science ...
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United States , Redmond
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102100.00 - 202200.00 USD / Year
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Microsoft Corporation
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Applied Scientist II and Senior
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Join Microsoft as an Applied Scientist II or Senior in Cambridge, MA, and drive AI innovation on Azure. You'll research and implement cutting-edge solutions using LLMs, deep learning, and statistical modeling. Ideal candidates hold a PhD or Master’s in CS or related field with 2+ years of experie...
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United States , Cambridge
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102100.00 USD / Year
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Microsoft Corporation
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Senior Applied Scientist and Principal Applied Scientist
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Join Microsoft’s Core AI Speech Group in Redmond as a Senior or Principal Applied Scientist. Drive innovation in end-to-end speech modeling, deep learning, and multimodal integration with LLMs. Requires a PhD/MS in CS, EE, or related field with experience in statistics and predictive analytics. I...
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United States , Redmond
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119800.00 USD / Year
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Microsoft Corporation
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Applied Scientist
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Join Microsoft’s EngOps as an Applied Scientist in Redmond, WA to drive AI-powered automation and enhance cloud reliability. You’ll lead ML projects from research to production, using LLMs/SLMs for intelligent reasoning. Requires a degree in CS, Statistics, or related field with internship experi...
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United States , Redmond
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102100.00 - 202200.00 USD / Year
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Microsoft Corporation
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Senior Applied Scientist
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Senior Applied Scientist role in Redmond, WA, driving AI-powered recommendation and generative systems across Microsoft’s consumer ecosystem (Edge, Windows, Copilot). Lead large-scale retrieval, deep ranking, and LLM-based personalization serving billions of daily requests. Requires expertise in ...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Applied Scientist
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Join Wayve Labs as an Applied Scientist to advance embodied AI for autonomous driving. Leverage expertise in world modeling, reinforcement learning, or spatial AI to develop next-gen systems. Based in Sunnyvale, CA, this role offers equity, relocation support, and collaboration with world-class r...
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United States , Sunnyvale
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Not provided
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Wayve
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Senior Applied Scientist, AWS Central Economics and Science
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Senior Applied Scientist role with AWS Central Economics & Science in San Francisco, New York, or Seattle. Leverage causal ML, neural deep learning, and Python to build models driving strategic decisions. Collaborate with stakeholders on incentive design and scientific rigor. Benefits include RSU...
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United States , San Francisco; New York; Seattle
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192200.00 - 260000.00 USD / Year
Amazon
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Applied Scientist II
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Join Microsoft’s Core Search and AI team in Redmond as an Applied Scientist II to build next-gen search with advanced LLMs and AI at scale. You will optimize retrieval, ranking, and relevance systems, refine RAG pipelines, and drive measurable impact. Requires a Bachelor’s in CS or related field ...
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United States , Redmond
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100600.00 - 199000.00 USD / Year
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Microsoft Corporation
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Senior Applied Scientist, Neuro-Symbolic AI Labs
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Join Amazon's Neuro-Symbolic AI Labs in Boston as a Senior Applied Scientist to build super-intelligent systems using proof assistants. You will define and implement scalable ML models, leveraging deep learning and Python/C++ expertise. Collaborate with top academia (MIT, Berkeley, CMU) and enjoy...
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United States , Boston
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167100.00 - 226100.00 USD / Year
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Amazon Pforzheim GmbH
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Principal Applied Scientist
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Join Microsoft AI as a Principal Applied Scientist in Redmond, WA, to architect next-gen recommendation systems using LLMs and GenAI. You will design deep learning ranking models and agentic systems for large-scale content feeds. Ideal for a senior leader with expertise in ML/DL pipelines and a P...
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United States , Redmond
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139900.00 - 304200.00 USD / Year
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Microsoft Corporation
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Senior Applied Scientist
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr. Applied Scientist, Road Safety
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United States , Seattle; San Francisco; Sunnyvale
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190000.00 - 211000.00 USD / Year
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Uber
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Applied Scientist, Marketing Measurement
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United States , New York; San Francisco
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161000.00 - 179000.00 USD / Year
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Uber
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Senior Applied Scientist (Bing Places)
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Data and Applied Scientist
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Join Microsoft’s Cloud Operations + Innovation team as a Data and Applied Scientist in Redmond, WA. Drive global cloud infrastructure decisions using statistical methods, machine learning, and causal inference. Build scalable BI solutions and data assets to optimize one of the world’s largest clo...
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United States , Redmond
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100600.00 - 199000.00 USD / Year
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Microsoft Corporation
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Principal Applied Scientist
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Join Microsoft’s Azure AI Foundry Agent Platform as a Principal Applied Scientist in Redmond, WA. Drive agent self-improvement by bridging research and production, leveraging RLHF and advanced AI. Requires a PhD/ Master’s in CS or related field with 3+ years of experience. Shape next-gen AI solut...
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United States , Redmond
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139900.00 - 304200.00 USD / Year
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Microsoft Corporation
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Principal Applied Scientist
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Lead AI innovation at Microsoft as a Principal Applied Scientist in Redmond. You will design and experiment with advanced LLM inference systems and robust evaluation frameworks. This role requires a strong background in AI/ML, predictive analytics, and experience with large-scale model fine-tunin...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Data Scientist - Applied AI Research
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Join our Westlake team as a Data Scientist in Applied AI Research. You will ideate and develop cutting-edge NLP and generative AI solutions, including LLMs and Agents. The role requires strong Python, PyTorch, and AWS skills to build and optimize models within an Agile framework. Collaborate clos...
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United States , Westlake
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Not provided
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Fidelity Investments
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About the Applied Scientist role

Applied Scientist jobs represent a dynamic and rapidly evolving career path at the intersection of cutting-edge research and real-world product development. Professionals in this role are responsible for translating complex theoretical concepts from machine learning, statistics, and computer science into scalable, production-ready systems that solve tangible business problems. Unlike pure research scientists, applied scientists focus on bridging the gap between academic advancements and practical implementation, ensuring that sophisticated algorithms deliver measurable impact in live environments.

The typical day-to-day work of an applied scientist involves designing, developing, and deploying machine learning models that power core features across diverse domains such as search engines, recommendation systems, advertising platforms, and natural language processing interfaces. Common responsibilities span the entire modeling lifecycle: from formulating research questions and designing training data strategies, to feature engineering, model architecture selection, and rigorous offline and online evaluation. Applied scientists often work closely with software engineers, product managers, and data engineers to integrate models into large-scale distributed systems, ensuring robust real-time inference, low latency, and high reliability. They also drive experimentation through A/B testing and statistical analysis, iterating on model performance based on user behavior and business metrics.

A strong foundation in quantitative disciplines is essential for these roles. Most applied scientist jobs require at least a Master’s degree, and often a PhD, in fields such as computer science, statistics, econometrics, electrical engineering, or a related quantitative domain. Candidates typically need several years of hands-on experience building machine learning models for business applications. Core technical skills include proficiency in programming languages like Python, C++, or Java; deep understanding of modern machine learning techniques including deep learning, transformers, generative AI, and reinforcement learning; and experience with large-scale data processing frameworks and tools. Expertise in information retrieval, natural language processing, recommendation systems, or agentic modeling is frequently sought after. Beyond technical prowess, applied scientists must possess strong analytical thinking, the ability to communicate complex findings to non-technical stakeholders, and a growth mindset that embraces continuous learning and innovation.

Applied scientist jobs are found across technology companies, e-commerce platforms, cloud service providers, and any organization leveraging AI to enhance user experiences or optimize operations. The role offers the unique opportunity to see your research directly influence products used by millions, making it a highly rewarding career for those passionate about both science and engineering. As the field of artificial intelligence continues to advance, the demand for skilled applied scientists who can turn theoretical breakthroughs into practical solutions will only grow. Whether you are working on improving search relevance, personalizing content, or building the next generation of conversational AI, applied scientist positions provide a challenging and impactful career path at the forefront of technological innovation.